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Pradeep Kumar Naik

faculty
Name : Prof.(Dr.) Pradeep Kumar Naik
Designation : Professor
Phone No. : 9479268802
Email Id : pknaik1973@gmail.com
Date of Birth : 09.04.1971
Date of Joining : 23.12.2015
Google Scholar : Browse

M.Sc, M.Phil, Ph.D, D.Sc in Life Sciences, P.G. Diploma in Bioinformatics

Biotechnology and Bioinformatics

  1. Professor, Department of Biotechnology & Bioinformatics, Sambalpur University, Odisha, India, 23rd December, 2015 to present
  2. Associate Professor, Department of Biotechnology, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur, Chhattisgarh, India, 7th February 2014 - 22nd December 2015
  3. Associate Professor, Department of Biotechnology & Bioinformatics, Jaypee University of Information Technology, Solan, Himachal Pradesh, India, 1st August 2011 - 5th Feb, 2014
  4. Assistant Professor, Department of Biotechnology & Bioinformatics, Jaypee University of Information Technology, Solan, Himachal Pradesh, India, 1st July 2008 – 31st July 2011
  5. Senior Lecturer, Department of Biotechnology & Bioinformatics, Jaypee University of Information Technology, Solan, Himachal Pradesh, India, 1st July 2005 – 30th June 2008
  6. Lecturer, Department of Biotechnology & Bioinformatics, Jaypee University of Information Technology, Solan, Himachal Pradesh, India, 3rd July 2003 – 30th June 2005
  7. BOYSCAST Fellow, Emory University School of Medicine, Atlanta, Georgia, USA, 26th July 2010 – 24th July 2011.
  8. Senior Research Fellow, CSIR, Sambalpur University, Odisha, India, 1st Dec 2000 – 31st Dec 2001
  9. Research Associate, ICAR, Sambalpur University, Odisha, India, Dec 1997 – Sept 1999
  10. Junior Research Fellow, ICAR, Sambalpur University, Odisha, India, Nov 1996 – Dec 1997

Post Graduate Level : M.Sc Biotechnology
M.Sc Bioinformatics

  1. Natural and value added product development for the therapeutic applications.
  2. Rational design and development of synthetic derivatives from natural lead (Noscapine) as potent tubulin-binding, less toxic, anti-cancer therapeutic agents.
  3. Natural products development for management of lymphatic filariasis, diabetics, malaria and bacterial infection.
  4. Assessment of genetic diversity of medicinal plants, phytochemical profiling of medicinal plants and product development for therapeutic application, DNA bar coding of plants and animal species.
  5. Protein modeling, computer aided molecules design, biological sequence analysis and clinical bioinformatics.

Ph.D. Candidates : 14
M.Tech./M.Phil. Candidates : 10

  1. Best Teacher’s Award, Sambalpur University, Odisha, 2021
  2. Recipient, BOYSCAST Fellowship, Govt. of India, Department of Science and Technology, 2009-10
  3. Recipient, Sarojini G. Panigrahi Young Scientist Award, Orissa Botanical Society, 1997
  4. CSIR-UGC Junior Research Fellowship and Eligibility for Lectureship (JRF-NET), 2001

  1. Nil

  1. CCRAS, Ministry of Ayush, Aqueous and hydroalcoholic extraction of selected anukta dravya plants and evaluation of their therapeutic efficacy for various diseases, Principal Investigator, Sanction No. 1258/2022-23, Dated: 16.02.2023, 115.84 Lakhs, 2023-2025 Ongoing
  2. CCRAS, Ministry of Ayush, Mechanistic studies in elucidation of shodhana for nine poisonous medicinal plants of E1 schedule, Principal Investigator, Sanction No. 1458/2022-23, Dated: 22.03.2023, 25.24 Lakhs, 2023-2026, Ongoing
  3. DBT, Govt. of India, DBT-BUILDER, Sambalpur University interdisciplinary Life Science programme for advanced research and education, Project Coordinator, Amount sanction: 534 Lakhs, 2021-2026
  4. OHEPEE, Govt. of Odisha, Centre of Excellence in Natural Products and Therapeutics, Project Coordinator, Amount Sanction: 400 Lakhs,2020-2025
  5. ICMR, Govt. of India, Optimization of natural anticancer agent, Noscapine by rational design of its derivatives: chemical synthesis and preclinical evaluation for the management of breast cancer. Principal Investigator, Sanction No. 5/13/11/2020-NCD-III, Dated: 22.03.2021, Sanction amount:48.41 Lakhs, March. 2021 to Jan. 2024
  6. ICMR, Govt. of India, Big data platform for temporal storage of clinical data of patients of cardiovascular diseases and data mining for better diagnosis and treatment. Principal Investigator, Sanction No. ISRM/12(129)/2020, Dated: 16.11.2020, Sanction amount: 21.15 Lakhs, Nov. 2020 to Oct. 2023
  7. ICMR, Govt. of India, Targeting specifically breast tumor cells by developing potent derivative of tubulin binding anticancer agent, noscapine and conjugating it with folic acid. Principal Investigator, Sanction No. 5/13/13/2019/NCD-III, Dated: 30.08.2019, Sanction amount: 51.0 Lakhs, Oct. 2019 to Sept. 2022
  8. DBT, Govt. of India, Development of synthetic derivatives of natural compound, Noscapine as tubulin binding chemotherapeutic agent and evaluation of its synergistic effect with Taxotere for management of human breast cancer. Principal Investigator, Sanction No. BT/PR24726/NER/95 833/2017, Date: 23.03.2018, Sanction amount: 75.0 lakhs March 2018 March 2021
  9. DST, Govt. of Odisha, Preclinical efficacy evaluation of extremely promising novel noscapinoid: A tubulin-binding agent in the management of breast cancer. Principal Investigator, Sanction No. 1207/ST, Bhubaneswar, Date: 01.03.2017, Sanction amount: 8.96 lakhs, July 2017-June 2020
  10. DBT, Govt. of India, Identification of intermediate metabolites for linking missing links in the biosynthetic pathways of desired chemical constituents in target plant species. Principal Investigator, Sanction amount: 68.65 lakhs, Sept. 2010 – Sept. 2015
  11. DRDO, Govt. of India, Toxicological evaluation of herbal formulations: (a) herbal performance enhancing capsules (PerfoMax), (b) herbal adaptogenic appetizer, (c) herbal tea and (d) seabuckthron oil based soft gel capsule. Principal Investigator, Sanction No. 118/6/JUIT-4/DIHAR, Date: 17.09.2013, Sanction amount: 8.49 lakhs, Sept. 2013- Sept. 2014
  12. DRDO, Govt. of India, Genetic characterization, chemical profiling and optimization of parameters for artemisinin yield in Artemisia annua from the Ladakh region. Principal Investigator, Sanction No. 118/6/JUIT/DIHAR, Date: 20.04.2009, Sanction amount: 9.50 lakhs,April 2009 - April 2011
  13. DST, Govt. of India, Study of population structure of Podophyllum hexandrum using biochemical and molecular markers. Principal Investigator, Sanction No. SR/FT/L-44/2005, Date: 22.02.2006, Sanction amount: 10.32 lakhs, Feb. 2006 - Feb. 2009

International Publications

    2023
  1. Pragyandipta P, Pedapati RK, Reddy PK, Nayek A, Meher RK, Guru SK, Kantevari S, Naik PK(2023). Rational design of novel microtubule targeting anticancer drugs N-imidazopyridine noscapinoids: Chemical synthesis and experimental evaluation based on in vitro using breast cancer cells and in vivo using xenograft mice model. Chemico-Biological Interactions, 382 (2023) 110606 https://doi.org/10.1016/j.cbi.2023.110606
  2. Behera S, Mohapatra S, Meher RK, Das PK, Babu SK, Naik M, Monalisa K, Naik SK, Naik PK (2023). Assessment of chemical composition and therapeutic activities of Clausena excavata Burn.: an important medicinal plant of Eastern Ghats India. Journal of Essential Oil Bearing Plants, 26 (2), https://doi.org/10.1080/0972060X.2023.2216721
  3. Kumar Pedapati, R., Pragyandipta, P., Pranathi Abburi, N., Chirra, N., Kantevari, S., & Naik, P. K. (2023). Antiproliferative Noscapinoids Bearing an Amidothiadiazole Scaffold as Apoptosis Inducers: Design, Synthesis and Molecular Docking. Chemistry & Biodiversity, 20(2), e202201089.
  4. Cheruvanachari P, Pattnaik S, Mishra M, Pragyandipta P, Pattnaik A, Naik PK (2023). Deciphering the antibioflim potential of 2-phenylethyl methyl ether (PEME), a bioactive compound of Kewda essential oil against Staphylococcus aureus. Microbial Pathogenesis, 179, doi.org/10.1016/j.micpath.2023.106093
  5. Cheruvanachari P, Mishra M, Pattnaik S, Naik PK (2023). Determination of antibacterial and antibioflim potential of Kewda essential oil against Staphylococcus aureus and Klebsiella pneumoniae. Biologia, https://doi.org/10.1007/s11756-023-01360-3
  6. Pragyandipta P, Naik MR, Bastia B, Naik PK. Development of 9-(N-arylmethylamino) congeners of noscapine: the microtubule targeting drugs for the management of breast cancer. 3 Biotech. 2023 Feb;13(2):38. doi: 10.1007/s13205-022-03445-3. Epub 2023 Jan 9. PMID: 36636578; PMCID: PMC9829942.
    7. 2022
  7. Pedapati RK, Chirra N, Abburi NP, Bollikonda R, Alekhya D, Sridhar B, Naik PK*, Kantevari S* (2022). Substrate-directed synthesis of isocoumarin and 3-ylidenephthalide conjugated noscapinoids and their antiproliferative activities. Chemistry An Asian Journal, doi.org/10.1002/asia.202201131. ISSN: 1861-471X
  8. Cheruvanachari P, Pattnaik S, Mishra M, Pragyandipta P, Naik PK (2022). Terpinen-4-ol, an active constituent of Kewda essential oil, mitigates biofilm forming ability of multidrug resistant Staphyococcus aureus and Klebsiella pneumoniae, 12, J. Biologically Act. Prod. Nat., 12(5): 406-420, doi: 10.1080/22311866 2022 2154264.
  9. Patra A, Satpathy S, Naik PK, Kazi M, Hussain MD (2022). Folate receptor-targeted PLGA-PEG nanoparticles for enhancing the activity of genistein in ovarian cancer. Artificial Cells, Nanomedicine and Biotechnology, 50(1): 228-239.DOI: 10.1080/21691401.2022.2118758
  10. Naik M, Behera S, Indur S, Babu SK, Naik PK (2022). Elemental, nutritional, phytochemical profiling and antioxidant activity of Cordia obliqua Willd (Clammy Cherry): an important underutilized forest tree of Eastern India. Journal of Applied Biology and Biotechnology Vol. 11(1), 195-199. DOI: 10.7324/JABB 2023.110127
  11. Champati BB, Padhiari BM, Ray A, Jena S, Sahoo A, Pattnaik J, Mohanty S, Naik PK, Panda PC, Nayak S (2022). Assessment of variation in shatavarin IV content in Asparagus racemosus through HPTLC analysis and identification of elite germplasm from Eastern India. Pharmacognosy Magazine. DOI: 10.4103/pm.pm_51_22
  12. Soppina P, Patel N, Shewale DJ, Rai A, Sivaramkrishnan S, Naik PK, Sopinna V (2022). Kinesin-3 motors are fine-tuned at the molecular level to endow distinct mechanical outputs. BMC Biology, 20:177, 1-23. https://doi.org/10.1186/s12915-022-01370-8
  13. Soppina P, Shewale DJ, Naik PK, Sopinna V (2022). Single-molecule analysis of Sf9 purified superprocessive kinesin-3 family motors. Jove Biochemistry, DOI: 10.3791/63837
  14. Behera S, Monalisa K, Meher RK, Mohapatra S, Madkami SK, Das PK, Naik PK, Naik SK (2022). Phytochemical fidelity and therapeutic activity of micropropagated Curcuma amada Roxb.: A valuable medicinal herb, Industrial Crops and Products, 176, https://doi.org/10.1016/j.indcrop.2021.114401 [ISSN 0926-6690]
  15. Padhiari BM, Ray A, Champati BB, Jena S, Sahoo A, Kuanar A, Halder T, Ghosh B, Naik PK, Patnaik J, Mohanty S, Panda PC, Nayak S (2022). Artificial neural network (ANN) modl for prediction and optimization of bacoside A content in Bacopa monnieri: a statistical approach and experimental validation. Plant Biosystem, https://doi.org/10.1080/11263504.2022.2048278
  16. Radha G, Naik PK, Lopus M (2022). In vitro characterization and molecular dynamic simulation of shikonin as a tubulin-targeed anticancer agent. Computers in Biology and Medicine, 147. doi.org/10.1016/j.compbiomed.2022.105789. [ISSN: 0010-4825]
  17. Behera S, Chauhan VBS, Pati K, Bansode V, Nedunchezhiyan M, Verma AK, Monalisa K, Naik PK, Naik SK (2022). Biology and biotechnological aspect of sweet potato (Ipomoea batatas L.): a commercially important tuber crop. Planta, 256:40. Doi.org/10.1007/s00425-022-03938-8. [ISSN: 0032-0935]
  18. Pragyandipta P, Meher RK, Nagireddy PKR, Pedapati RK, Kantevari S, Naik PK* (2022). Structure based design of tubulin binding 9-arylimino noscapinoids: chemical synthesis and experimental validation against breast cancer cell lines. Analytical Chemistry Letters, 12(1): 29-43. DOI: 10.1080/22297928.2021.2009029. [ISSN: 2229-7928]
  19. Kumar R, Salar RK, Naik PK, Yadav M, Kumar A, Kumar A, Yogi R, Kumar M, Chhokar V (2022). Elucidation of genetic diversity and population structure of sixty genotypes of Aloe vera using AFLP markers. South African Journal of Botany, 147: 1146-1155. https://doi.org/10.1016/j.sajb.2021.06.008 [ISSN: 0254-6299]
    20. 2021
  20. Dash SG, Kantevari S, Guru SK, Naik PK* (2021). Combination of docetaxel and newly synthesized 9-Br-trimethoxybenzyl noscapine improve tubulin binding and enhances antitumor activity in breast cancer cells. Computers in Biology and Medicine, 139, 104996, doi: 10.1016/j.compbiomed.2021.104996. [ISSN: 0010-4825]
  21. Sahoo PK, Aparna S, Naik PK, Singh SB, Das SK (2021). Bisphenol A exposure induces neurobehavioral deficits and neurodegeneration through induction of oxidative stress and activated caspase-3 expression in zebrafish brain. Journal of Biochemical and Molecular Toxicology, 35(10): e22873, doi: 10.1002/jbt.22873. [ISSN: 1099-0461]
  22. Meher RK, Pragyandipta P, Pedapati RK, Nagireddy PKR, Kantevari S, Nayek AK, Naik PK* (2021). Rational design of novel N-alkyl amine analogues of noscapine, their chemical synthesis and cellular activity as potent anticancer agents. Chemical Biology and Drug Design, DOI: 10.1111/cbdd.13901. [ISSN: 1747-0285]
  23. Dash SG, Kantevari S, Pandey SK, Naik PK* (2021) Synergistic interaction of N-3-Br-benzyl-noscapine and docetaxel abrogates oncogenic potential of breast cancer cells. Chemical Biology and Drug Design DOI: 10.1111/cbdd.13902. [ISSN: 1747-0285]
  24. Patel AK, Meher RK, Nagireddy PK, Pedapati RK, Pragyandipta P, Kantevari S, Naik MR, Naik PK* (2021) Rational design, chemical synthesis and cellular evaluation of novel 1,3-diynyl derivatives of noscapine as potent tubulin binding anticancer agents. Journal of Molecular Graphics and Modelling, 106, 107933 doi: 10.1016/j.jmgm.2021.107933 [ISSN: 1093-3263]
  25. Dash SG, Kantevari S, Naik PK* (2021) Combination regimen of amino-noscapine and docetaxel for evaluation of anticancer activity. 10.1080/22297928.2021.1896380 UGC Approved, Analytical Chemistry Letter, 11(2), 215-229. [ISSN: 2229-7928]
  26. Pragyandipta P, Meher RK, Naik MR, Nagireddy PKR, Pedapati RK, Kantevari S, Naik PK* (2021) In silico inspired design of 1,3-diynyl congeners of noscapine as promising tubulin binding anticancer agent: chemical synthesis and cellular activity with breast cancer cell lines. Chemistry Select, 6, 3500-3511. doi.org/10.1002/slct.202004723. [ISSN: 2365-6549]
  27. Patel AK, Meher RK, Nagireddy PK, Pragyandipta P, Pedapati RK, Kantevari S, Naik PK* (2021) 9-Arylimino noscapinoids as potent tubulin binding anticancer agent: chemical synthesis and cellular evaluation against breast tumour cells. SAR and QSAR in Environmental Research, doi: 10.1080/ 1062936X.2021.1891567. [ISSN: 1029-046X]
  28. Meher RK, Nagireddy PKR, Pragyandipta P, Kantevari S, Singh SK, Kumar V, Naik PK*(2021) In silico design of novel tubulin binding 9-arylimino derivatives of noscapine, their chemical synthesis and cellular activity as potent anticancer agents against breast cancer. Journal of Biomolecular Structure and Dynamics, Feb. 25, 1-12. doi: 10.1080/07391102.2021.1889668. [ISSN: 0739-1102]
  29. Anothra P, Pradhan D, Naik PK, Ghosh G, Rath G (2021). Development and characterization of 5-fluorouracil nanofibrous film for the treatment of stomach cancer. Journal of Drug Delivery Science and Technology, 61, February, 102219. doi.org/10.1016/j.jddst.2020.102219, [ISSN: 1773-2247]
  30. Induar S, Behera BC, Dubey D, Naik PK (2021). Proximate and sensory properties of Dioscorea bulbifera composite flour made cookies and cake. Asian Journal of Biological and Life Sciences, DOI: 10.5530/ajbls.2020.9. [ISSN: 2278-5957]
  31. Rajendran SS, Naik PK, Shankar S, Subramanian U, Asaithambi N (2021). A mixed analysis on coping and social support needs of breast cancer survivors in Chennai, India. Psychology and Education 58(2):9158-9169. DOI: 10.17762/pae.v58i2.3620 [ISSN: 0033-3077]
  32. Rajendran SS, Naik PK, Shankar S, Subramanian U, Asaithambi N (2021). A mixed analysis on coping and social support needs of breast cancer survivors in Chennai, India. Psychology and Education 58(2):9158-9169. DOI: 10.17762/pae.v58i2.3620 [ISSN: 0033-3077]
  33. Rajendran SS, Naik PK, Shankar S, Asaithambi N, Arunachalam SS, Periasamy G, Natesan M (2021). Female breast cancer survivor’s perspectives on hope and spirituality needs-a mixed study approach. Psychology and Education 58(2): 9771-9780.DOI: 10.17762/pae.v58i2.3835 [ISSN: 0033-3077]
  34. Rajendran SS, Naik PK, Asaithambi N, Shankar S (2021). Impact of selected perceived needs on quality of life of breast cancer survivors. Annals of Romanian Society for Cell Biology 25(4): 850-859. [ISSN: 2067-3019]
  35. Rajendran SS, Naik PK, Subramaniam R, Asaithambi N, Shankar S (2021). Perceived need experience of breast cancer survivors seeking health care – a qualitative approach. Psychology and Education 58(3): 3361-3367. DOI: 10.17762/pae.v58i3.4495 [ISSN: 0033-3077]
  36. 30. Rajendran SS, Naik PK, Arunachalam SS (2021). Scientometrics of the emerging trends in nursing research related to perceived needs of breast cancer survivors. Biosc. Biotech. Res. Comm. 14(1): 435-440. [ISSN: 0974-6455]
  37. Rajendran SS, Naik PK, Venkatesan A, Asaithambi N, Murugesan K, Shankar S, Arunachalam SS (2021). A descriptive analysis of the psychosocial status of breast cancer survivors from Chennai, India. Biosc. Biotech. Res. Comm. 14(1): 382-386. [ISSN: 0974-6455]
    38. 2020
  38. Sahu DK, Pradhan D, Naik PK, Kar B, Ghosh G, Rath G (2020). Smart polymeric eye gear: A possible preventive measure against ocular transmission of COVID-19. Medical Hypothesis 144, 110288. doi: 10.1016/j.mehy.2020.110288 [ISSN: 0306-9877]
  39. Pradhan D, Biswasroy P, Naik PK, Ghos G, Rath G (2020). A review of current interventions for COVID-19 prevention. Archives of Medical Research, 51(5): 363-374. DOI: 10.1016/j.arcmed.2020.04.020. [ISSN: 0188-4409]
  40. Kumar A, Naik PK, Pradhan D, Ghos G, Rath G (2020). Mucoadhesive formulations: innovations, merits, drawbacks and future outlook. Pharmaceutical Development and Technology, 25(7): 797-814. DOI: 10.1080/10837450.2020.1753771 [ISSN: 1083-7450]
  41. Dash SG, Suri C, Nagireddy PKR, Kantevari S, Naik PK* (2020) Rational design of 9-vinyl-phenyl noscapine as potent tubulin binding anticancer agent and evaluation of the effects of its combination on docetaxel. Journal of Biomolecular Structure and Dynamics, Jul 1, 1-14. doi: 10.1080/07391102.2020.1785945. [ISSN: 0739-1102]
  42. Rajendran SS, Naik PK, Arunachalam SS (2020). A psychosocial wellbeing of breast cancer survivors – an overview of evidence base nursing research. European Journal of Molecular & Clinical Medicine 7(3): 4834-4841. [ISSN: 2515-8260]
  43. Rajendran SS, Naik PK, Kasinathan K, Murudan A, Ibrahim R, Asaithambi N (2020). Sleep quality, fatigue and medication adherence among breast cancer survivors at Chennai - a descriptive study. European Journal of Molecular & Clinical Medicine 7(3): 1426-1439. [ISSN: 2515-8260]
  44. Rajendran SS, Naik PK, Asaithambi N, Arunachalam SS, Shankar S, Venkatesan A (2020). Sociodemographic status of breast cancer survivors in Chennai. Biosc. Biotech. Res. Comm. 13(10): 315-321. [ISSN: 0974-6455]
  45. Rajendran SS, Naik PK, Arunachalam SS, Asaithambi N, Shankar S (2020). Psychosocial wellbeing status of breast cancer survivours – an observational study. Biosc. Biotech. Res. Comm. 13(10): 322-327.[ISSN: 0974-6455]
    46. 2018
  46. Pradhan M, Suri C, Choudhary S, Naik PK, Lopus M (2018) Elucidation of the anticancer potential and tubulin isotype-specific interactions of β-sitosterol. Journal of Biomolecular Structure and Dynamics, 36(1):195-208. DOI: 10.1080/07391102.2016.1271749 [ISSN: 0739-1102]
  47. Kumari P, Dixit V, Tiwari AK, Saxena S, Vishvakarma NK, Naik PK, Shukla D (2018) Computer assisted designing of triazole derivative of noscapine as tubulin binding anticancer drug. Asian Journal of Pharmaceutical and Clinical Research, 11(2): 69-75. DOI: 10.22159/ajpcr.2018.v11s2.28586 [ISSN: 2455-3891]
  48. Bastia B, Kumar K, Kumar SN, Naik PK, Behera NR, Jain AK (2018). Image segmentation and association analysis of endothelin-1 and CD-31 expression in tobacco smokers’ placenta using automated nearest neighbour and genetic algorithm. Journal of Biological Sciences and Medicine, 4(1): 1-9. [ISSN: 2455-5266]
    49. 2017
  49. Mahaddalkar T, Naik PK, Choudhary S, Manchukonda N, Kantevari S, Lopus M (2017) Structural investigations into the binding mode of a novel noscapine analogue, 9-(4-vinylphenyl) noscapine, with tubulin by biochemical analyses and molecular dynamic simulations. Journal of Biomolecular Structure and Dynamics, 35(11): 2475-2484. DOI: 10.1080/07391102.2016.1222969 [ISSN: 0739-1102]
    50. 2016
  50. Akbar A, Kuanar A, Joshi AK, Sandeep IS, Mohanty S, Naik PK, Mishra A, Nayak S (2016). Development of prediction model and experimental validation in predicting the curcumin content of turmeric (Curcuma longa L.). Frontiers in Plant Sciences, Vol 7, Article 1507, DOI: 10.3389/fpls.2016.01507. DOI: 10.3389/fpls.2016.01507 [ISSN: 1664-462X]
  51. Sandeep IS, Kuanar A, Akbar A, Kar B, Das S, Mishra A, Sial P, Naik PK, Nayak S, Mohanty S (2016) Agroclimatic zone based metabolic profiling of turmeric (Curcuma longa L.) for phytochemical yield optimization. Industrial Crops and Products, 85: 229-240. DOI: 10.1016/j.indcrop.2016.03.007 [ISSN: 0926-6690]
  52. Kumar M, Naik PK, Patlan S, Chhokar V (2016) Assessment of genetic variation among Asparagus racemosus genotypes using molecular marker and biochemical markers. Journal of Medicinal Plants Studies, 4(6): 117-123. [ISSN 2320-3862]
    53. 2015
  53. Santoshi S, Manchukonda NK, Suri C, Sridhar B, Joseph S, Lopus M, Kantevari S, Baitharu I, Naik PK* (2015) Rational design of biaryl pharmacophore inserted noscapine derivatives as potent tubulin binding anticancer agents. Journal of Computer Aided Molecular Design, 29: 249-270. DOI: 10.1007/s10822-014-9820-5 [ISSN: 0920-654X]
  54. Mahaddalkar T, Suri C, Naik PK, Lopus M (2015) Biochemical characterization and molecular dynamic simulation of β-sitosterol as a tubulin-binding anticancer agent. European Journal of Pharmacology, 760: 154-162. DOI: 10.1016/j.ejphar.2015.04.014. [ISSN: 0014-2999]
  55. Suri C, Joshi HC, Naik PK* (2015) Molecular modeling reveals binding interface of γ-tubulin with GCP4 and interactions with noscapinoids. Proteins: Structure, Functions and Bioinformatics, 83: 827-843. DOI: 10.1002/prot.24773. [ISSN: 0887-3585]
  56. Suri C, Naik PK* (2015) Combined molecular dynamics and continuum solvent approaches (MM-PBSA/GBSA) to predict noscapinoid binding to γ-tubulin dimer. SAR & QSAR Environmental Research, 26(6): 507-519. DOI: 10.1080/1062936X.2015.1070200 [ISSN: 1062-936X]
  57. Das P, Mohanty S, Swain D, Sahoo P, Das G, Naik PK, Hota SK, Bordoloi MJ, Rao HBDP (2015) Typhonium trilobatum (L.) Schott shows potency against lymphatic filariasis in man. International Journal of Indigenous Medicinal Plants, 48(1): 1821-1826. [ISSN: 2051-4263]
  58. Aggarwal H, Rao A, Kumar A, Singh J, Rana JS, Naik PK, Chhokar V (2015) Assessment of genetic diversity among 125 cultivars of Chickpea (Cicer arietinum L.) of Indian origin using ISSR markers. Turkish Journal of Botany, 39: 218-226. DOI:10.3906/bot-1401-80 [ISSN: 1300-008]
  59. Singh C, Pradhan JK, Singh S, Thakur A, Naik PK, Singh H (2015) Biosynthesis and antibacterial activity of silver and gold nanoparticles using Liquorice root: A green chemistry approach. Journal of Colloidal Science and Biotechnology, 4(2): 147-152. DOI:10.1166/jcsb.2015.1128 [ISSN: 2164-9642]
  60. Aggarwal H, Rao A, Kumar A, Singh J, Rana JS, Naik PK, Chhokar V (2015) Evaluation of genetic divergence and phylogenetic relationship using sequence-tagged microsatellite (STMS) sequences in Chickpea (Cicer arietinum L.) genotypes. African Journal of Biotechnology, 14(45): 3051-3061. DOI: 10.5897/AJB2015.14827. [ISSN: 1684-5315]
    61. 2014
  61. Suri S, Hendrickson TW, Joshi HC, Naik PK* (2014) Molecular insight into γ-γ tubulin lateral interactions within the γ-tubulin ring complex (γ-TuRC). Journal of Computer Aided Molecular Design, 28(9): 961-972. DOI: 10.1007/s10822-014-9779-2. [ISSN:0920-654X]
  62. Santoshi S, Naik PK* (2014) Molecular insight of isotypes specific β-tubulin interaction of tubulin heterodimer with noscapinoids. Journal of Computer Aided Molecular Design 28:751-763. DOI: 10.1007/s10822-014-9756-9. [ISSN: 0920-654X]
  63. Manchukonda NK, Naik PK, Sridhar B, Kantevari S (2014) Synthesis and biological evaluation of novel biaryl type α-noscapine congeners. Bioorganic & Medicinal Chemistry Letters, 24(24): 5752-5757. DOI: 10.1016/j.bmcl.2014.10.046 [ISSN: 0960-894X]
  64. Lopus M, Naik PK (2014). Taking aim at a dynamic target: noscapinoids as microtubule-targeted cancer therapeutics. Pharmacological Reports, 67: 56-62. DOI: 10.1016/j.pharep.2014.09.003 [ISSN: 1734-1140]
  65. Baitharu I, Jain V, Deep SN, Naik PK, Ilavazhagan G (2014) Withanolide A prevent neurodegeneration by modulating hippocampal glutathione biosynthesis during hypoxia. PLoS One, 9(10): e105311. DOI: 10.1371/journal.pone.0105311. [ISSN: 1932-6203]
  66. Raghu R, Devaraji V, Leena K, Riyaz SD, Rani PB, Kumar SB, Naik PK, Dubey PK, Velmurugan D, Vijayalakshmi M (2014) Virtual screening and discovery of novel aurora kinase inhibitors. Current Topics in Medicinal Chemistry, 14: 2006-2019. DOI: 10.2174/1568026614666140929151140. [ISSN: 1568-0266]
    67. 2013
  67. Manchukonda NK, Naik PK*, Santoshi S, Lopus M, Joseph S, Sridhar B, Kantevari S (2013) Rational design synthesis and biological evaluation of third generation α-noscapine analogues as potent tubulin binding anti-cancer agents. PLoS One, 8(10):e77970. DOI: 10.1371/journal.pone.0077970. [ISSN:1932-6203]
  68. Singh NB, Singh MK, Naik PK, Thakur S, Sharma JP (2013) Analysis of genetic diversity in female, male and half sibs willow genotypes through RAPD and SSR markers. African Journal of Biotechnology, 12(29):4578-4587. DOI: 10.5897/AJB2013.12120 [ISSN: 1684-5315]
  69. Sengupta D, Naik PK* (2013) SN algorithm: analysis of temporal clinical data for mining periodic patterns and impending augury. Journal of Clinical Bioinformatics, 3(14): 1-7. doi: 10.1186/2043-9113-3-24 [ISSN: 2043-9113]
  70. Aggarwal KP, Tandon S, Naik PK, Singh SK, Tandon C (2013) Peeping into human renal calcium oxalate stone matrix: characterization of novel proteins involved in the intricate mechanism of urolithiasis. PLoS One, 8(7): e69916. DOI: 10.1371/journal.pone.0069916. [ISSN: 1932-6203]
  71. Aggarwal KP, Tandon S, Naik PK, Singh SK, Tandon C (2013) Novel antilithiatic cationic proteins from human calcium oxalate renal stone matrix identified by MALDI-TOF-MS endowed with cytoprotective potential: An insight into the molecular mechanism of urolithiasis. Clinica Chimica Acta, 415: 181-190. DOI: 10.1016/j.cca.2012.10.040. [ISSN: 0009-8981]
  72. Kar B, Nanda S, Naik PK, Nayak S, Joshi RK (2013) Molecular characterization and functional analysis of CzR1, a coiled-coil nucleotide binding site leucine rich repeat R-gene from Curcuma dezoaria (Loeb.) that confers resistance to Pythium aphanidermatum. Physiological and Molecular Plant Pathology, 83: 59-68. DOI: 10.1016/j.pmpp.2013.05.003 [ISSN: 0885-5765]
  73. Sengupta D, Sood M, Vijayvargia P, Hota S, Naik PK* (2013) Association rule mining based study for identification of clinical parameters akin to occurrence of brain tumor. Bioinformation, 9 (11): 555-559. doi: 10.6026/97320630009555 [ISSN: 0973-2063]
  74. Sengupta D, Arora P, Pant S, Naik PK* (2013) Design of dimensional model for clinical data storage and analysis. Applied Medical Informatics, 32(2): 47-53. [ISSN: 1224-5593]
    75. 2012
  75. Naik PK*, Lopus M, Aneja R, Vangapandu SN, Joshi HC (2012) In silico inspired design and synthesis of a novel tubulin-binding anti-cancer drug: folate conjugated noscapine (Targetin). Journal of Computer Aided Molecular Design, 26(2): 233-247. DOI: 10.1007/s10822-011-9598-z. [ISSN: 0920-654X]
  76. Manchukonda NK, Sridhar B, Naik PK, Joshi HC, Kantevari S (2012) Copper(I) mediated facile synthesis of potent tubulin polymerization inhibitor, 9-amino-α-noscapine from natural α-noscapine. Bioorganic Medicinal Chemistry Letter, 22(8): 2983-2987. DOI: 10.1016/j.bmcl.2012.02.033 [ISSN: 0960-894X]
  77. Naik PK*, Santoshi S, Joshi HC (2012) Noscapinoids with anti-cancer activity against human acute lymphoblastic leukemia cells (CEM): a three dimensional chemical space pharmacophore modeling and electronic feature analysis. Journal of Molecular Modeling, 18(1): 307-318. DOI: 10.1007/s00894-011-1057-9 [ISSN: 1610-2940]
  78. Gupta N, Naik PK, Chauhan RS (2012) Differential transcript profiling through cDNA-AFLP showed complexity of rutin biosynthesis and accumulation in seeds of a nutraceutical food crop (Fragopyrum spp.). BMC Genomics, 13(1): 231- 240. DOI: 10.1186/1471-2164-13-231 [ISSN: 1471-2164]
  79. Pandit S, Shitiz K, Sood H, Naik PK, Chauhan RS (2012) Expression pattern of fifteen genes of non-mevalonate (MEP) and mevalonate (MVA) pathways in different tissues of endangered medicinal herb Picrorhiza kurroa with respect to picrosides content. Molecular Biology Report, 40(2): 1053-1063. DOI: 10.1007/s11033-012-2147-1 [ISSN: 0301-4851]
  80. Singh C, Baboota RK, Naik PK, Singh H (2012) Biocompatible synthesis of silver and gold nanoparticles using leaf extract of Dalbergia sissoo. Advanced Materials Letters, 3(4):279-285. DOI: 10.5185/amlett.2011.10312 [ISSN: 0976-3961]
  81. jain S, Naik PK*, Bhooshan SV (2012) Compendium model of AKT for cell survival/death and its equivalent bio-circuit. International J. of Soft Computing and Engineering, 2(3): 91-97. [ISSN: 2231-2307]
    82. 2011
  82. Naik PK*, Chatterji BP, Vangapandu SN, Aneja R, Chandra R, Kanteveri S, Joshi HC (2011) Rational design, synthesis and biological evaluations of amino-noscapine: a high affinity tubulin-binding noscapinoid. Journal of Computer Aided Drug Design, 25(5): 443-454. DOI: 10.1371/journal.pone.0077970 [ISSN: 0920-654X]
  83. Naik PK*, Santoshi S, Rai A, Joshi HC (2011) Molecular modelling and competition binding study of Br-noscapine and colchicine provide insight into noscapinoid-tubulin binding site. Journal of Molecular Graphics and Modeling, 29(7): 947-955. DOI: 10.1016/j.jmgm.2011.03.004 [ISSN: 1093-3263]
  84. Santoshi S, Naik PK*, Joshi HC (2011) Rational design of novel anti-microtubule agent (9-azido-noscapine) from quantitative structure activity relationship (QSAR) evaluation of noscapinoids. Journal of Biomolecular Screening, 16(9):1047-1058. DOI: 10.1177/1087057111418654 [ISSN: 1087-0571]
  85. Bhoyar MS, Mishra GP, Naik PK*, Srivastava RB (2011) Estimation of antioxidant activity and total phenolics among natural populations of Capparis spinosa leaves collected from cold arid desert of trans-Himalayas. Australian Journal of Crop Sciences, 5(7): 912-919. [ISSN: 1835-2693]
  86. Kumar J, Singh H, Mishra GP, Srivastava RB, Naik PK* (2011) Genetic analysis of Artemisia annua genotypes using RAPD and ISSR molecular markers from the trans-Himalayan (Ladakh, India) region. Journal of Medicinal Plant Research, 5(23):5568-5576. [ISSN: 1996-0875
  87. Singh C, Sharma V, Naik PK, Khandelwal V, Singh H (2011) A green biogenic approach for synthesis of gold and silver nanoparticles using Zingiber officinale. Digest Journal of Nanomaterials and Biostructures, 6(2): 535-542. [ISSN: 1842-3582]
  88. Kumar J, Mishra GP, Naik PK*, Murkute AA, Srivastava RB (2011) Genomic DNA isolation from Artemisia species grown in cold desert high altitude of India. African Journal of Biotechnology, 10(37): 7303-7307. [ISSN: 1684-5315]
  89. Naik PK*, Srivastava M, Bajaj P, Jain P, Dubey A, Ranjan P, Kumar R, Singh H (2011) The Binding modes and binding affinities of artemisinin derivatives with Plasmodium falciparum Ca2+-ATPase (PfATP6). Journal of Molecular Modeling, 17(2): 333-357. DOI: 10.1007/s00894-010-0726-4 [ISSN: 1610-2940, IF: 1.984]
  90. Naik PK*, Ranjan P, Kesari P, Jain S (2011). MetalloPred: A tool for hierarchical prediction of metal ion binding proteins using cluster of neural networks and sequence derived features. Journal of Biophysical Chemistry, 2(2): 112-123. DOI: 10.4236/jbpc.2011.22014 [ISSN: 2153-036X]
  91. Jain S, Bhoosan SV, Naik PK* (2011) Mathematical modeling deciphering balance between cell survival and cell death using insulin. Network Biology, 1(1): 46-58. DOI:10.0000/issn-2220-8879-networkbiology-2011-v1-0004 [ISSN: 2220-8879]
  92. Pathak P, Naik PK, Sengupta D, Singh SK, Tandon C (2011) Mode of interaction of calcium oxalate crystal with human phosphate cytidyltransferase 1: a novel inhibitor purified from human renal stone matrix. Journal of Biomedical Science and Engineering, 4:591-598. DOI: 10.4236/jbise.2011.49075 [ISSN:1937-6871]
  93. Pani A, Mahapatra RK, Behera N, Naik PK (2011) Computational identification of sweet wormwood (Artemisia annua) microRNA and their mRNA targets. Genomics Proteomics Bioinformatics, 9(6): 200-210. DOI: 10.1016/S1672-0229(11)60023-5 [ISSN: 1672-0229]
    94. 2010
  94. Naik PK*, Alam MA, Malhotra A, Rizvi O (2010) Molecular Modeling and Structure-activity relationship of the podophyllotoxin and its congeners. Journal of Biomolecular Screening, 15(5): 528-540. DOI: 10.1177/1087057110368994 [ISSN: 1087-0571]
  95. Naik PK*, Alam MA, Singh H, Goyal V, Parida S, Kalia S, Mohapatra T (2010) Assessment of genetic diversity through RAPD, ISSR and AFLP markers in Podophyllum hexandrum: a medicinal herb from the Northwestern Himalayan region. Physiology and Molecular Biology of Plants, 16(2): 1-14. DOI: 10.1007/s12298-010-0015-9 [ISSN: 0971-5894]
  96. Soni K, Rawat S, Gupta A, Yangzom K, Pandit S, Naik PK, Singh H (2010) Genetic characterization of Rhodiola rosea using gene specific SSR and CAPS molecular markers. Genetic Engineering and Biotechnology Journal, GEBJ-11. [ISSN: 2150-3516]
  97. Naik PK*, Dubey A, Soni K, Kumar R, Singh H (2010) The binding modes and binding affinities of epipodophyllotoxin derivatives with human topoisomerase IIα. Journal of Molecular Graphics and Modeling, 29(4): 546-564. DOI: 10.1016/j.jmgm.2010.10.005 [ISSN: 1093-3263]
  98. Jaiswal K, Kumar C, Naik PK* (2010) Prediction of EF-hand calcium-binding proteins and identification of calcium-binding regions using machine learning techniques. Journal of Cell and Molecular Biology, 8(2): 41-49. . [ISSN: 1303-3646]
  99. Naik PK*, Alam MA, Malhotra A, Rizvi O (2010) Molecular Modeling and Structure-activity relationship of the podophyllotoxin and its congeners. Journal of Biomolecular Screening, 15(5): 528-540. [ISSN: 1087-0571]
  100. Naik PK*, Dubey A, Kumar R (2010) Development of predictive quantitative structure activity relationship models of epipodophyllotoxin derivatives. Journal of Biomolecular Screening, 15(10): 1194-1203. DOI: 10.1177/1087057110380743 [ISSN: 1087-0571]
  101. Jain S, Naik PK*, Bhooshan SV (2010) A system model for cell death/survival using SPICE and Ladder logic. Digest Journal of Nanomaterials and Biostructures, 5(1):57-66. [ISSN:1842-3582]
  102. Patel AK, Patel S, Naik PK (2010) Prediction and classification of DNA binding proteins into four major classes based on simple sequence derived features using ANN. Digest Journal of Nanomaterials and Biostructures, 5(1): 191-200. [ISSN: 1842-3582]
  103. Naik PK*, Santoshi S, Birmani A (2010) Computational prediction of potent therapeutic targets of Pseudomonas aeruginosa and in silico virtual screening for novel inhibitors. Internet Electronic Journal of Molecular Design, 8: 42–62. [ISSN: 1538-6414]
    104. 2009
  104. Alam MA, Naik PK* (2009) Molecular modeling evaluation of the cytotoxic activity of podophyllotoxin analogues. Journal of Computer Aided Molecular Design, 23(4): 209-225. DOI: 10.1007/s10822-008-9252-1 [ISSN: 0920-654X]
  105. Alam MA, Naik PK* (2009) Applying linear interaction energy method for binding affinity calculations of podophyllotoxin analogues with tubulin using continuum solvent model and prediction of cytotoxic activity. Journal of Molecular Graphics & Modeling, 27(8): 930-943. DOI: 10.1016/j.jmgm.2009.02.003 [ISSN: 1093-3263]
  106. Alam MA, Naik PK*, Mishra GP (2009) Congruence of RAPD and ISSR markers for evaluation of genomic relationship among 28 populations of Podophyllum hexandrum from Himachal Pradesh, India. Turkish Journal of Botany, 33: 1-12. DOI: 10.3906/BOT-0711-10 [ISSN: 1300-008X]
  107. Alam MA, Naik PK* (2009) Impact of soil nutrients and environmental factors on podophyllotoxin content among 28 Podophyllum hexandrum populations of Northwestern Himalayan region using linear and non-linear approach. Communication in Soil Science and Plant Analysis, 40: 2485-2504. DOI: 10.1080/00103620903111368 [ISSN: 0010-3624]
  108. Alam MA, Naik PK* (2009) Molecular modeling evaluation of the cytotoxic activity of podophyllotoxin analogues. Journal of Computer Aided Molecular Design, 23(4): 209-225.DOI: 10.1007/s10822-008-9252-1 [ISSN: 0920-654X]
  109. Alam MA, Naik PK* (2009) Applying linear interaction energy method for binding affinity calculations of podophyllotoxin analogues with tubulin using continuum solvent model and prediction of cytotoxic activity. Journal of Molecular Graphics & Modeling, 27(8): 930-943. DOI: 10.1016/j.jmgm.2009.02.003 [ISSN: 1093-3263]
  110. Srivastava M, Singh H, Naik PK* (2009) Application of the linear interaction energy method for rational design of artemisinin analogues as haeme polymerization inhibitors. SAR and QSAR in Environmental Research, 20(3-4): 327-355. DOI: 10.1080/10629360902949294 [ISSN: 1062-936X]
  111. Naik PK, Patel A (2009) Prediction of anticancer/non-anticancer drugs based on comparative molecular moment descriptors using artificial neural network and support vector machine. Digest Journal of Nanomaterials and Biostructures, 4(1): 19-43. [ISSN: 1842-3582]
  112. Srivastava M, Singh H, Naik PK* (2009) Quantitative structure-activity relationship (QSAR) of artemisinin: development of predictive in vitro antimalarial activity models. Journal of Chemometrics, 23(11-12): 618-635. DOI:10.1002/cem.1261 [ISSN: 0886-9383]
  113. Naik PK*, Sindhura, Singh T, Singh H (2009) Quantitative structure-activity relationship (QSAR) for insecticides: development of predictive in vivo insecticide activity models. SAR and QSAR in Environmental Research, 20(5-6): 551-566. DOI: 10.1080/10629360903278735 [ISSN: 1062-936X]
  114. Patel AK, Patel S, Naik PK (2009) Binary classification of uncharacterized proteins into DNA binding/non-DNA binding proteins from sequence derived features using ANN. Digest Journal of Nanomaterials and Biostructures, 4(4): 775-782. [ISSN: 1842-3582]
  115. Naik PK*, Sindhura, Singh T, Singh H (2009) Quantitative structure-activity relationship (QSAR) for insecticides: development of predictive in vivo insecticide activity models. SAR and QSAR in Environmental Research, 20(5-6): 551-566. DOI: 10.1080/10629360903278735. [ISSN: 1062-936X, IF: 1.667]
  116. Jain S, Naik PK*, Sharma R (2009) A computational model for cell survival/death using VHDL and MATLAB simulator. Digest Journal of Nanomaterials and Biostructures, 4(4): 863-879. [ISSN: 1842-3582, IF: 1.092]
    117. 2008
  117. Alam MA, Naik PK*, Gulati P, Gulati AK, Mishra GP (2008) Characterization of genetic structure of Podophyllum hexandrum populations–an endangered medicinal herb of Northwestern Himalaya using ISSR-PCR markers and its relatedness with podophyllotoxin content. African Journal of Biotechnology, 7(8): 1028-1040. [ISSN: 1684-5315]
  118. Gupta S, Srivastava M, Mishra GP, Naik PK*, Chauhan RS, Tiwari KS, Kumar M, Singh R (2008) Analogy of ISSR and RAPD markers for comparative analysis of genetic diversity among different Jatropha curcas genotypes. African Journal of Biotechnology, 7(23): 4230-4243. [ISSN: 1684-5315]
  119. Sengupta D, Verma D, Naik PK* (2008) Docking-MM-GB/SA and ADME screening of HIV-1 NNRTI inhibitor: nevirapine and its analogues. In Silico Biology, 8(3-4): 275-289. [ISSN: 1386-6338]
    120. 2007
  120. Tandon C, De Lisle RC, Boulatnikov I, Naik PK (2007) Interaction of carboxyl-terminal peptides of cytosolic-tail of apactin with PDZ domains of NHERF/EBP50 and PDZK-1/CAP70. Molecular and Cellular Biochemistry, 302: 157-167. DOI: 10.1007/s11010-007-9437-2 [ISSN: 0300-8177]
    121. 2006
  121. Nayak S, Naik PK, Acharya LK, Pattnaik AK (2006) Detection and evaluation of genetic variation in 17 promising cultivars of turmeric (Curcuma longa L.) using 4C nuclear DNA content and RAPD markers. Cytologia, 71(1): 49-55. DOI: 10.1508/cytologia.71.49 [ISSN: 0011-4545
  122. Nayak S, Naik PK (2006) Factors effecting in vitro microrhizome formation and growth in Curcuma longa L. and improved field performance of micropropagated plants. Science Asia, 32: 31-37. DOI:10.2306/scienceasia1513-1874.2006.32.031 [ISSN: 1513-1874]
    123. 2005
  123. Naik PK, Nayak S (2005) Different modes of plant regeneration and factors effecting in vitro bulblet production in Ornithogalum virens. Science Asia, 31: 409-414. DOI:10.2306/scienceasia1513-1874.2005.31.409 [ISSN: 1513-1874]
  124. Nayak S, Naik PK, Acharya LK, Mukhaerjee AK, Panda PC, Das P (2005) Assessment of genetic diversity among 16 promising cultivars of ginger using cytological and molecular markers. Z. Naturforsch, 60c: 485-492. doi: 10.1515/znc-2005-5-618. [ISSN: 0939-5075]
    125. 2000
  125. Mohapatra PK, Naik PK, Patel R (2000) Ethylene inhibitors improve dry matter partitioning and development of late flowering spikelets on rice panicles. Australian Journal of Plant Physiology, 27: 311-323. DOI: 10.1071/PP99057 [ISSN: 1445-4408]
  126. Naik PK*, Mohapatra PK (2000) Ethylene inhibitors enhanced sucrose synthase activity and promoted grain filling of basal rice kernels. Australian Journal of Plant Physiology, 27: 39 - 51. DOI:10.1071/PP00020 [ISSN: 1445-4408]
    127. 1999
  127. Naik PK*, Mohapatra PK (1999) Ethylene inhibitors promote male gametophyte survival in rice. Plant Growth Regulation, 28: 29-39. DOI: 10.1023/A:1006285615853 [ISSN: 0167-6903]

National Publications

    2020
  1. Naik PK, Dubey D, Cheruvanachari P, Pattnaik A, Babu SK (2020), In vitro evaluation of antibacterial and antioxidant properties of an Indian medicinal plant: Celastrus paniculatus. Journal of Biomedical and Pharmaceutical Research, 9(1): 98-104. DOI:10.32553/jbpr.v9i1.726 [ISSN: 2278-5957]
    2. 2018
  2. Meher RK, Naik MR, Bastia B, Naik PK* (2018) Comparative evaluation of anti-angiogenic effects of noscapine derivatives. Bioinformation, 14(5): 236-240. DOI: 10.6026/97320630014236 [ISSN: 0973-2063]
  3. Bhoyar MS, Mishra GP, Naik PK, Singh SB (2018) Evaluation of antioxidant capacities and total polyphenols in various edible parts of Capparis spinosa L. collected from trans-Himalayas. Defense Life Sciences Journal, 3(2): 140-145. DOI: 10.14429/dlsj.3.12570 [ISSN: 2456-379X]
    4. 2016
  4. Kumar R, Naik PK, Kumar A, Aggarwal H, Kumar A and Chhokar V (2016) A combined approach using RAPD, ISSR and bioactive compound for the assessment of genetic diversity in Aloe vera (L.) Burn.f. Indian Journal of Biotechnology, 14: 538-549. [ISSN: 0972-5849]
  5. Rani S, Kumar M, Naik PK, Phulia SK and Chhokar V (2016). ESRα exon polymorphism coupled with protein modeling in relation to reproductive traits in murrah buffaloes. International Journal of Pharma and Bio Sciences, 7(4): 856-868. DOI:10.22376/ijpbs.2016.7.4.b856-868
    6. 2014
  6. Kumar J, Bajaj P, Mishra GP, Singh SB, Singh H, Naik PK* (2014) Utilization of EST-derived SSRs in the genetic characterization of Artemisia annua L. genotypes from Ladakh, India. Indian Journal of Biotechnology, 13: 464-472. [ISSN: 0972-5849]
    7. 2013
  7. Joshi RK, Nanda S, Rout E, Kar B, Naik PK, Nayak S (2013) Molecular modeling and docking characterization of CzR1, a CC-NBS-LRR gene from Curcuma dezoaria (Loeb.) that confers resistance to Pythium aphanidermatum. Bioinformation, 9(11): 560-564. DOI: 10.6026/97320630009560. [ISSN: 0973-2063]
  8. Sharma M, Naik PK* (2013) The mode and mechanism of interaction of angiopoietin II with receptor tyrosine kinase (Tie-2) using molecular mechanics and molecular dynamics approach. International J. Fundamental & Applied Science, 2(1): 8-11. [ISSN: 2278-1404]
    9. 2012
  9. Bhoyar MS, Mishra GP, Naik PK*, Murkute AA, Srivastava RB (2012) Genetic variability studies among natural populations of Capparis spinosa from cold arid desert of trans-Himalayas using DNA markers. National Academic Science Letter, 35(6): 505-515. DOI: 10.1007/s40009-012-0086-y [ISSN:0250-541X]
  10. Kumar J, Mishra GP, Murkute AA, Kumar GP, Naik PK*, Srivastava RB (2012) Exploring genetic relationships in Artemisia species growing in trans-Himalayan cold arid desert using RAPD markers. Indian Journal of Horticulture, 69(2):239-245. [ISSN: 0972-8538]
  11. Kumar J, Bajaj P, Singh H, Mishra GP, Singh SB, Naik PK* (2012) Utilization of Intron-flanking EST-specific markers in the genetic characterization of Artemisia annua genotypes from the trans-Himalayan region of Ladakh, India. Journal of Environmental Biology, 33, 991-997. [ISSN: 0254-8704]
  12. Gupta S, Bhoyar MS, Kumar J, Warghat AR, Bajpai PK, Rasool M, Mishra GP, Naik PK, Ravi BS (2012) Genetic diversity among natural populations of Rhodiola imbricata Edgew. from trans- Himalayan cold arid desert using random amplified polymorphic DNA (RAPD) and inter simple sequence repeat (ISSR) markers. Journal of Medicinal Plant Research, 6(3): 405-415. DOI: 10.5897/JMPR11.1064 [ISSN: 1996-0875]
  13. Mahapatra RK, Behera N, Naik PK* (2012) Molecular modeling and evaluation of binding mode and affinity of artemisinin-quinine hybrid and its congeners with Fe-protoporphyrin-IX as a putative receptor. Bioinformation, 8(8): 369-380. doi: 10.6026/97320630008369 [ISSN: 0973-2063]
  14. Mahapatra RK, Behera N, Naik PK* (2012) Molecular modelling and prediction of binding mode and relative binding affinity of Art-Qui-OH with P. falciparum Histo-Aspartic Protease (HAP). Bioinformation, 8(17): 827-833. DOI: 10.6026/97320630008827 [ISSN: 0973-2063]
  15. Santoshi S, Naik PK* (2012) A field based 3D QSAR model of novel anti-microtubule agent noscapine and its derivatives. International Journal of Fundamental and Applied Sciences, 1(2): 81-87. [ISSN: 2278-1404]
  16. Suri C, Naik PK* (2012) Elucidating the precise interaction of reduced and oxidized states of neuroglobin with Ubc12 and Cop9 using molecular mechanics studies. International Journal of Fundamental and Applied Sciences, 1(2): 74-77. [ISSN: 2278-1404]
  17. Kumar A, Kumar R, Beniwal V, Kala SN, Mishra A, Raut AA, Naik PK*, Chhokar V (2012) Molecular differentiation of peroxysome proliferator activated receptor coactivator-1 among different breeds of Bubalus bubalis. Bioinformation, 8(13): 600–606. DOI: 10.6026/97320630008600 [ISSN: 0973-2063]
  18. Jain S, Ranjan P, Sengupta D, Naik PK* (2012) TpPred: A tool for hierarchical prediction of transport proteins using cluster of neural networks and sequence derived features. International Journal of Computational Biology, 1(1): 46-60. DOI: 10.34040/IJCB.1.2012.18 [ISSN: 2278-8115]
  19. Suri C, Naik PK* (2012) Elucidating the precise interaction of reduced and oxidized states of neuroglobin with Ubc12 and Cop9 using molecular mechanics studies. International Journal of Fundamental and Applied Sciences, 1(2): 74-77. [ISSN: 2278-1404]
  20. Jain S, Naik PK* (2012) System modelling of cell survival and cell death: A deterministic model using Fuzzy system. International Journal of Pharma and Bio Sciences, 3(4): 358-373. [ISSN: 0975-6299]
  21. Jain S, Bhooshan SV, Naik PK* (2012) Communication of signals and responses leading to cell death using engineered regulatory networks. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 3(3): 492-508. [ISSN: 0975-8585]
  22. Kumar A, Chhokar V, Kumar R, Beniwal V, Kala SN, Mishra A, Raut AA, Naik PK (2012) Molecular differentiation of mitochondrial glycerol-3-phosphate acyltransferase among different breeds of Bubalus bubalis. International Journal of Pharma and Bio Sciences, 3(4): (B) 685-694. [ISSN: 0975-6299]
    23. 2011
  23. Jain S, Naik PK*, Bhooshan SV (2011) A computational model for cell survival/death using petrinets. International Journal of Applied Engineering Research, 6(5): 545-552. [ISSN: 0973-4562]
  24. Jain S, Bhooshan SV, Naik PK* (2011) Mathematical modeling deciphering balance between cell survival and cell death using tumor necrosis factor α. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 2(3): 574-583. DOI:10.0000/issn-2220-8879-networkbiology-2011-v1-0004 [ISSN: 0975-8585]
    25. 2010
  25. Jain S, Bhooshan SV, Naik PK* (2010) Model of mitogen activated protein kinases for cell survival/death and its equivalent bio-circuit. Current Research Journal of Biological Sciences, 2(1): 59-71. [ISSN: 2041-0778]
  26. Srivastava M, Singh H, Naik PK* (2010) Molecular modeling evaluation of the antimalerial activity of artemisinin analogues: molecular docking and rescoring using Prime/MM-GBSA approach. Current Research Journal of Biological Sciences, 2(2): 83-102. [ISSN: 2041-0778]
  27. Naik PK*, Santoshi S, Birmani A (2010) Computational prediction of potent therapeutic targets of Pseudomonas syringae and in silico virtual screening for novel inhibitors. International Journal of Pharma and Bio Sciences, 1(2): 1-23. [ISSN: 0975-6299]
  28. Jain S, Naik PK*, Bhooshan SV (2010) Petri net implementation of cell signaling for cell death. International Journal of Pharma and Bio Sciences, 1(2): 1-18. [ISSN: 0975-6299]
  29. Patel AK, Patel S, Naik PK (2010) Assessment of molecular binding of podophyllotoxin analogues into ATPase domain of topoisomerase II using docking-MM-GB/SA approach. Current Research Journal of Biological Sciences, 2(1): 13-23. [ISSN: 2041-076X]
  30. ain S, Bhooshan SV, Naik PK* (2010) Caspase: leads to apoptosis using VHDL and SPICE. International Journal of Electronics and Computers, 2(1): 9-17. [ISSN: 0975-3796]
  31. Jain S, Naik PK*, Bhooshan SV (2010) Computational modeling of cell survival/death using BiCMOS. International Journal of Computer Theory and Engineering, 2(4): 478-481. DOI:10.7763/IJCTE.2010.V2.188 [ISSN: 1793-8201]
  32. Jain S, Naik PK* (2010) Computational modeling of cell survival using VHDL. BVICAM,s. International Journal of Information Technology, 2: 47-51. [ISSN: 0973-5658]
  33. Jain S, Naik PK* (2010) Computational modeling of cell survival using VHDL. BVICAM,s. International Journal of Information Technology, 2: 47-51. [ISSN: 0973-5658]
    34. 2009
  34. Kumar M, Mishra GP, Singh R, Kumar J, Naik PK, Singh SB (2009) Correspondence of ISSR and RAPD markers for comparative analysis of genetic diversity among different apricot genotypes from cold arid deserts of trans-Himalayas. Physiology & Molecular Biology of Plants, 15(3): 225-236. DOI: 10.1007/s12298-009-0026-6 [ISSN: 0971-5894]
  35. Alam MA, Gulati AK, Mishra GP, Naik PK* (2009) Assessment of genetic diversity among Podophyllum hexandrum genotypes of the North-western Himalayan region for podophyllotoxin production. Indian Journal of Biotechnology, 8: 391-399. [ISSN: 0972-5849]
  36. Kumar M, Mishra GP, Singh R, Naik PK*, Dwivedi S, Ahmed Z, Singh SB (2009) Genetic variability studies among apricot populations from cold arid desert of Ladakh using DNA markers. Indian Journal of Horticulture, 66(2): 147-153. [ISSN: 0972-8538]
  37. Kumar M, Mishra GP, Singh R, Naik PK*, Dwivedi S, Ahmed Z, Singh SB (2009) Genetic variability studies among apricot populations from cold arid desert of Ladakh using DNA markers. Indian Journal of Horticulture, 66(2): 147-153. [ISSN: 0972-8538, IF: 0.125]
  38. Jain S, Naik PK*, Sharma R (2009) A computational modeling of apoptosis signaling using VHDL and MATLAB simulator. International J. of Information and Communication Technology, 2(1-2):7-12. [ISSN: 1466-6642]
    39. 2008
  39. Naik PK*, Mittal VK, Gupta S (2008) RetroPred: a tool for prediction, classification and extraction of non-LTR retrotransposons (LINEs & SINEs) from the genome by integrating PALS, PILER, MEME and ANN. Bioinformation, 2(6): 263-270. DOI:10.6026/97320630002263 [ISSN: 0973-2063]
  40. Jaiswal K, Naik PK* (2008) Distinguishing compounds with anticancer activity by ANN using inductive QSAR descriptors. Bioinformation, 2(10):441-451. doi: 10.6026/97320630002441 [ISSN: 0973-2063]
    41. 2007
  41. Sengupta D, Verma D, Naik PK* (2007) Docking mode of delvardine and its analogues into P66 domain of HIV-1 reverse transcriptase: screening using MM-GB/SA and ADME properties. Journal of Biosciences, 32(7): 1307-1316. doi: 10.1007/s12038-007-0140-y. [ISSN: 0250-5991]
  42. Naik PK*, Mishra VS, Gupta M, Jaiswal K (2007) Prediction of enzymes and non-enzymes from protein sequence based on sequence derived features and PSSM matrix using artificial neural network. Bioinformation, 2(3): 107-112. DOI: 10.6026/97320630002107 [ISSN: 0973-2063]

Mucoadhesive Gargle Composition And A Method of Preparation Thereof. Amresh Kumar, Dr. Goutam Ghosh, Dr. Pradeep Kumar Naik, Dr. Goutam Rath, Department of Pharmaceutics, SOA University and Department of Pharmacognosy, Department of Biotechnology and Bioinformatics, Sambalpur University, Application No. 201931046226, Date of Publish: 21.05.2021, Indian Patent Journal Issue: 21/2021

  1. Pattnaik S, Mishra M, Singh H, Naik PK (2023). Novel perspectives on phytochemicals-based approaches for mitigation of biofilms in ESKAPE pathogens: Recent trends and future avenues. Book Title: Recent Frontiers of Phytochemicals: Applications in Food, Pharmacy, Cosmetics and Biotechnology pp 433-454, Publisher: Elsevier
  2. Mishra M, Pattnaik S, Singh H, Naik PK (2023). Exploring the role of Mahua as a functional food and its future perspectives. Book Title: Recent Frontiers of Phytochemicals: Applications in Food, Pharmacy, Cosmetics and Biotechnology, pp 109-121, Publisher: Elsevier
  3. Dash SG, Joshi HC, Naik PK* (2022). Noscapinoids: A Family of Microtubule-Targeted Anticancer Agent. Springer Nature, Singapore, A. N. Grace et al. (eds.), Handbook of Porous Carbon Materials
  4. Sengupta D, Sharma VK, Hota SK, Srivastava RB, Naik PK (2021) An ensemble approach for evaluating the cognitive performance of human population at high altitude. In Machine Learning, Big dad and IoT for Medical Informatics, Academic Press, Elsevier, UK, [ISBN: 978-o-12-821777-1] Pp. 165-175
  5. Pradhan S, Naik PK*, Biswal D, Behera A, Pati SS, Mishra S (2018) Mangroves Atlas of Bhitarkanika. Ekamra Press, Bhubaneswar, [ISBN: 978-93-5321-684-9]
  6. Naik PK*, Dash AK (2015) Ascertain genetic diversity of Artemisia annua adapted to harsh environment of Ladakh using RAPD and ISSR molecular markers. Advances in Environmental Sciences and Engineering, Daya Publishing House, Astral International pvt. Ltd., New Delhi, pp. 406-428. [ISBN-9789351243366]
  7. Naik PK*, Shri Ram, Singh H (2011) Population structure and molecular characterization of Podophyllum hexandrum of the northwestern Himalayas. In: Medicinal Plant Biotechnology, Edited by Rajesh Arora, C.A.B Interrnational, UK, pp. 267-276. (ISBN-9781845936785)
  8. Joshi HC, Salil A, Bughani U, Naik PK (2011) Noscapinoids: A new class of anti-cancer drugs demand biotechnological intervention. In: Medicinal Plant Biotechnology, Edited by Rajesh Arora, C.A.B. Interrnational, UK, (2011), pp. 303-320. [ISBN-9781845936785, Citation: 5]
  9. Mishra GP, Singh RK, Naik PK, Singh R, Singh SB (2008) Advances in Molecular Breeding: An Introduction. In: Molecular Plant Breeding: Principle Methods and Applications, Edited by R. K. Singh, Studium Press LLC, Texas, USA, pp. 1-34. [ISBN-1933699493]

  1. Workshop on Animal Cell Culture Techniques and Screening of Drug Molecules from 10th Oct. to 16th Oct. 2022 under DST-STUTI Programme
  2. Entrepreneurship development programme for 06 months on "development of value added food products from Mahua flowers and Moringa, funded by DBT, Govt. of India

  1. Head, Dept. of Biotechnology and Bioinformatics
  2. Dean of Science and Technology
  3. Director, Research and Development Cell
  4. Director, Incubation Centre
  5. Coordinator, COE-NPT
  6. Coordinator, DBT-BUILDER
  7. Coordinator M.Sc Bioinformatics
  8. Coordinator Food Science and Technology
  9. Members of various committees

DATA TO BE UPDATED...

Present Address : 
Department of Biotechnology and Bioinformatics, Sambalpur University, Jyoti Vihar - 768 019, Burla, Sambalpur, Odisha		   Permanent Address : 
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