"DBT Builder National Facility" DBT-BUILDER, Sambalpur University Interdisciplinary Life Sciences Programme for Advance Research and Education has been established at Department of Biotechnology and Bioinformatics, Sambalpur University, Fuunded by Department of Biotechnology, Government of India from April, 2022.
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC) WITH PDA, FLUROSCENCE AND RI DETECTOR
Model: HPLC System – Alliance e2695 Separation Module PDA Detector – 2998 PDA FLR Detector – 2475 FLR RI Detector – 2414 RI
Make: Waters Corporation, USA
Uses:
Quantitative and qualitative estimation of Ayurvedic, Herbal, Synthetic, Pharmaceutical, Neutraceuticals and cosmeceuticals samples. Detection of impurities in drug substances. Analysis of carbohydrates, and amino acids in plant and food samples. Analysis of vitamins. Preservative analysis in drug formulations, cosmeceuticals and neutraceuticals. Monitoring the levels of pollutants in water and soil.
HIGH RESOLUTION MASS SPECTROMETER (HRMS) QUADRUPOLE-TIME OF FLIGHT MASS SPECTROMETER
Model: UPLC System – Acquity I-Class Plus Mass Detector – Xevo G3 QTof
Make: Waters Corporation, USA
Uses:
Phytochemical screening of drug metabolites from plant, animal and marine origin. Quantitative estimation of high and even low sensitive compounds in Ayurvedic, Herbal, Synthetic, Pharmaceutical, Neutraceuticals and cosmeceuticals preparations. Analyzing plant matrix, complex food or water samples for pesticides, mycotoxins etc. or equally challenging human or animal urine analysis samples for poisons or drugs. Identifying compounds relevant for dynamic metabolic processes; including sample preparation, data acquisition and data evaluation.
GAS CHROMATOGRAPHY MASS SPECTOMETRY (GC-MS)
Model:Nexis GC-2030 & GCMS-QP2020 NX
Make: Shimadzu, Japan
Uses:
GC-MS used for routine analysis looking for volatile contaminants with a molecular weight of usually less than 700 amu, for example in the food,2 environmental,5 forensics,6 anti-doping7 and consumer products8 industries. GC-MS is also used in research to identify unknown volatile compounds, including in food and flavors, space, petrochemical, chemical, agriculture, tobacco, pharmaceutical, healthcare, energy, mining, environmental and forensics to name but a few.
MICOWAVE EXTRACTION SYSTEM (FOR ESSENTIAL OIL EXTRACTION) WITH CHILLER
Model:ETHOS X
Make: Milestone, Italy
Uses:
Extraction of Flavor and Fragrances from aromatic plants. Extraction of essential oils from flowers, leaf, rhizomes, petals, peels, bark, etc.
Virtual Tour to DBT-Builder National Laboratory Facility in Department of Biotechnology and Bioinformatics, Sambalpur University.